The Carolina Nanoformulation Workshop is a unique training workshop about nanotechnology-based approaches to address pharma and biopharma needs for delivery of clinically relevant molecules. The workshop takes place at the Eshelman School of Pharmacy at the University of North Carolina at Chapel Hill.
Topics covered include:
- Challenges and opportunities in drug delivery
- Safety, regulation and characterization
- Materials and fabrication approaches
- Overcoming barriers in nanomedicine delivery
- Translational aspects
- Nanotechnology assembly and characterization techniques
The virtualCNW (Carolina Nanoformulation Workshop) is a unique training opportunity that addresses key drug delivery issues relevant to both industrial and academic scientists. In this online training workshop, state-of-the-art pre-clinical/clinical stage nanotechnologies will be comprehensively analyzed to provide “real-life” examples and rationale for using nanoformulations to tackle drug delivery issues and explore strategies to obtain proof-of-concept in a clinical trial. Many promising drug candidates that show excellent activity in in vitro screening assays do not advance to the preclinical development stage for multiple reasons including lack of efficacy, toxicity, poor absorption; distribution; metabolism and elimination (ADME) properties, suboptimal pharmacokinetic (PK) and biodistribution profiles ultimately leading to drug molecule attrition rates. Formulation and Drug Delivery is one viable strategy that can address each of these challenges and possibly improve the translation of drug molecules from bench-to-bedside to improve therapeutic outcomes and decrease patient suffering.
The workshop will train industrial and academic scientists on the comprehensive spectrum of considerations and issues involved in the process of developing a nanoformulated drug at the bench to obtaining regulatory approval for its clinical use. The instructors at the virtualCNW have diverse backgrounds including material science and engineering, bioengineering, chemistry, biochemistry, biology, pharmaceutics, and clinical research. The goal of the virtualCNW is to create a strong well-trained workforce of next generation scientists with common interest in the area of nanomedicine and drug delivery to share knowledge and advance the field.